There is one domain in Meursault that stands out for both its quality and resulting worldwide reputation: Domaine des Comtes Lafon. Established at the beginning of the 19th century by a wealthy amateur called Jules Lafon, the house is today directed by his great grandson, Dominique Lafon. It uses the same family traditions and covers 13 appellations. The domain has for a long time aimed to preserve the environment in its winemaking process. It now uses biodynamics and was officially classified "organic" in 1998.

The name "Désiré" comes from an official name which ceased to be used in 1973. As the name has a much longer history with Comtes Lafon, the domaine is authorised to continue to label its wine with the name. It is a superb Meursault; the most accessible in the whole range. Unlike the domaine's other wines, there is no need to wait ten years before drinking. It is immediately attractive, with beautiful substance; tender and well balanced.