There is one domain in Meursault that stands out for both its quality and resulting worldwide reputation: Domaine des Comtes Lafon. Established at the beginning of the 19th century by a wealthy amateur called Jules Lafon, the house is today directed by his great grandson, Dominique Lafon. It uses the same family traditions and covers 13 appellations. The domain has for a long time aimed to preserve the environment in its winemaking process. It now uses biodynamics and was officially classified "organic" in 1998.

The Volnay Premier Cru from the Comtes Lafon estate is made from plots of land in the appellation of Santenots (Santenots-du-Milieu). Planted across clay soil over an underbed of limestone, these vines produce wines that are particularly rich and dense for a Volnay, with an intersting structure combined with great finesse.