Established in 1868 in the small commune of Auxey-Duresses, the Leroy House owes its success to Henry Leroy, who started working in the family business in 1919. In 1942 he purchased 50% of the Romanée-Conti vineyards, which the family still owns with the Villaine family. Since 1955, his daughter Marcelle - who is nicknamed Lalou - is at the head of the domain. She relates that her father poured a drop of Musigny wine on her lips at her birth. Between 1985 and 1989, in order to produce the best wines, she bought the vines from the Noëllat and Philippe Rémy domains with the help of her Japanese importer to found the Domaine Leroy. Today Lalou Bize-Leroy is at the head of an extraordinary wine property of 22.4 hectares covering 24 appellations. No compromise for Leroy wines: biodynamics and extremly small yields. If the wines of the trading house are very popular, the wines of the domain are cult since they embody, with the DRC, what's best from Burgundy. The reputation of the domain has gone way beyond the French boundaries and it is now extremely difficult to get hold of one of these prestigious bottles.

The domaine owns three climats in Nuits Saint-Georges: "Aux Allots", "Aux Lavières" and "Bas de Combe". In 2008, low output meant that all production was sold under the Nuits Saint-Georges label, with no reference to individual climat.