Founded in 1957 by the Chivas Brothers group, the Glen Keith distillery was, in its early days, designed to trial new ideas. Originally equipped for triple distillation, it was also the first to install a gas-fired still system, developed its own strains of yeast and produced a peated single malt named Glenisla. The distillery was mothballed in 1999 and then bought by Pernod Ricard, who updated the distillery and relaunched production in 2013.

A Glen Keith 22 year old distilled in 1967 and bottled at cask strength in 1989 for the Prestonfield range. Signatory Vintage was founded in 1988 by Andrew Symington, who previously worked at Prestonfield House, Edinburgh, where he would select casks specially for the hotel. In 2002, he bought the Edradour distillery in Pitlochry, in the Highlands of Scotland and moved Signatory Vintage vintage to the site, including the warehouses opposite the distillery.