Built at the end of the 18th century, Uitvlugt is located on the western bank of the River Demerara, near the town of the same name founded by Dutch settlers in 1752. Nationalized in 1979 like many of the country's other distilleries, it was part of Demerara Distillers Ltd. until it closed in 1999. Although many distillations were completed in a Savalle still, Uitvlugt was also home to a Coffey still, a Versailles wood single pot still after Enmore closed in 1994, and a double pot still, also wooden, which is now kept at Port Mourant. After the distillery closed, all the distillation equipment was moved to Diamond, the country's last operating distillery.

A single cask Uitvlugt 20 year old (#19) distilled in 1998 and bottled in 2018 by Silver Seal for the Rum Is Nature range. Silver Seal was founded in 2000 by Ernesto Mainardi—also the founder of Sestante—and bought in 2010 by Massimo Righi, the owner of Whisky Antique. A limited edition of 215 bottles to support the Rock No War! project for Zimbabwe.